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Fluocinonide

Fluocinonide is a synthetic glucocorticoid and derivative of fluocinolone acetonide with anti-inflammatory and antipruritic activities. Fluocinonide is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis.


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Fluocinolone

Fluocinolone binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Fluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization. It was patented in 1958 and approved for medical use in 1961.


SynZeal offers allFluocinolone related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Fluocinolone related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.


Fesoterodine

Fesoterodine also known as toviaz, belongs to the class of organic compounds known as diphenylmethanes. Fesoterodine is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. It was approved by the European Medicines Agency in April 2007


SynZeal offers all Fesoterodine related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Fesoterodine related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.


Exemestane

Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Exemestane is a drug which is used for the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy. FDA approval was in October 2005.


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Ezetimibe

Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous sitosterolemia (phytosterolemia). Ezetimibe was approved for medical use in the United States in 2002.


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Etonogestrel

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.Etonogestrel is a drug which is used for use as a female contraceptive. Etonogestrel was patented in 1972 and introduced for medical use in 1998.


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Etodolac

Etodolac is a pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. Etodolac used for the management of mild to moderate pain, fever, and inflammation. It was patented in 1971 and approved for medical use in 1985.


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Ethinylestradiol

Ethinylestradiol is a semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. Ethinylestradiol medication which is used widely in birth control pills in combination with progestins. Ethinylestradiol was developed in the 1930s and was introduced for medical use in 1943.


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Erythromycin

Erythromycin is a broad-spectrum, macrolide antibiotic with antibacterial activity. Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and gram-negative bacteria. Erythromycin was first isolated in 1952 from the bacteria Saccharopolyspora erythraea.


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